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India: Novo Nordisk's Indian patent application was rejected in 2019 on grounds of obviousness (the Indian Patent Office ruled that semaglutide was an obvious modification of liraglutide)

(2020) 63:e20190538

People with Kidney Disease : Supplements like creatine , high doses of protein powder , and calcium can strain the kidneys, especially in individuals with pre-existing kidney conditions

The Svensson group built an artificial intelligence pipeline they called Peptide Predictor and trained it on a question the field had not previously known how to ask in a systematic way: of all the human protein-coding genes, which encode short peptides that look, by structural and contextual signature, like they should be acting as endogenous appetite-modulating signals

H., Zhang, S., & Song, Y